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2020

Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GerparNuevo

Karn, T., et al. Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GerparNuevo. Annals of Oncology 2020 May 24; https://doi.org/10.1016/j.annonc.2020.05.015. In Press, Journal Pre-proof Online.

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Sarcomatoid Renal Cell Carcinoma Demonstrates an Immunosuppressive Tumor Microenvironment - Implication for Therapeutic Benefit in the Immunotherapy Era

Hwang, M., et al. Sarcomatoid Renal Cell Carcinoma Demonstrates an Immunosuppressive Tumor Microenvironment - Implication for Therapeutic Benefit in the Immunotherapy Era.  Poster session presented at: United Sstates and Canadian Academy of Pathology (USCAP) 109th Annual Meeting 2020 FEB 29- MAR 5, Los Angeles, CA

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2019

Pre-therapeutic PD-L1 expression and dynamics of Ki-67 and gene expression during neoadjuvant immune-checkpoint blockade and chemotherapy to predict response within the GeparNuevo trial

Sinn, B.V., et al. Pre-therapeutic PD-L1 expression and dynamics of Ki-67 and gene expression during neoadjuvant immune-checkpoint blockade and chemotherapy to predict response within the GeparNuevo trial. Abstract PD5-05 presented at: American Association for Cancer Research Breast Symposium; December 4-8, 2019. San Antonio, Texas.

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2018

Randomized phase II neoadjuvant study (GepartNuevo) to investigate the addition of durvalumab to a taxane-anthracycline containing chemotherapy in triple negative breast cancer (TNBC)

Loibl, S., et al. Randomized phase II neoadjuvant study (GepartNuevo) to investigate the addition of durvalumab to a taxane-anthracycline containing chemotherapy in triple negative breast cancer (TNBC). Clinical Science Symposium Presented at: American Society of Clinical Oncology (ASCO); 2018 June 2, Chicago, IL.

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Targeted mRNA sequencing using small formalin-fixed, paraffin-embedded core biopsies to evaluate immune and tumor-associated gene expression in breast cancer

Sinn, B. V., et al Targeted mRNA sequencing using small formalin-fixed, paraffin embedded core biopsies to evaluate immune and tumor-associated gene expression in breast cancer. Abstract presented at: 102nd Annual Meeting of the German Society for Pathology 2018 May 24 – 16; Berlin, Germany, Abstract #AG13.03

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Fibroblast growth factor receptor 3 (FGFR3), peroxisome proliferator-activated receptor gamma (PPARg), and outcomes with nivolumab (nivo) in metastatic urothelial cancer (UC).

Galsky, M. et al. Fibroblast growth factor receptor 3 (FGFR3), peroxisome proliferator-activated receptor gamma (PPARg), and outcomes with nivolumab (nivo) in metastatic urothelial cancer (UC). Poster session presented at: Genitourniary Cancers Symposium; 2018 Feb 9; San Francisco, CA. J Clin Oncol 36, 2018 (suppl 6S; abstr 511).

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2017

Advanced molecular characterization of severe autoimmune toxicities associated with checkpoint inhibitor therapies

Balko J., et al. Advanced molecular characterization of severe autoimmune toxicities associated with checkpoint inhibitor therapies. Poster session presented at: The American Association for Cancer Research, 2017 Apr; Washington, DC

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Heterogeneity in immune biomarker expression after acquisition of resistance to EGFR kirase inhibitors: Analysis of a case with small cell lung cancer transformation

Suda et. al. Heterogeneity in immune biomarker expression after acquisition of resistance to EGFR kirase inhibitors: Analysis of a case with small cell lung cancer transformation; J Thorac Oncol. 2017 Jun; 1216: 1015 

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