Assays
HTG EdgeSeq Mouse mRNA Tumor Response Panel

HTG EdgeSeq Mouse mRNA Tumor Response Panel

Measure 1,659 mouse mRNA targets in one RNA extraction-free assay. The HTG EdgeSeq Mouse mRNA Tumor Response Panel leverages the sensitivity and dynamic range of next-generation sequencing (NGS) to measure genes implicated in preclinical mouse models of human disease.

Built around core signaling pathways and immune response mechanisms in oncology and other disease states, the HTG EdgeSeq Mouse mRNA Tumor Response Panel enables multiplex profiling from a variety of sample types, including a single section of formalin-fixed, paraffin-embedded (FFPE) tissue, cell lines, and extracted RNA samples. Applications include modeling oncogenesis, studying the immune response to mouse and patient-derived xenografts, and investigational therapeutic response studies. HTG’s extraction-free HTG EdgeSeq assays are automated on the HTG EdgeSeq system or can be run in HTG’s VERI/O service laboratory.

For Research Use Only. Not for Use in Diagnostic Procedures.

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Features and Benefits

  • Measure 1,659 transcripts in a single well: obtain a broad profile of genes associated with oncology, immunity, and inflammation
  • Extraction-free chemistry: the simple workflow reduces extraction-associated data bias and sample loss
  • Low sample input: reliable, reproducible performance from a single section of FFPE tissue
  • Simplified data analysis: analyze results in the HTG EdgeSeq Reveal Data Suite, not a complicated RNASeq pipeline

 

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Sample Requirements

Sample Type HTG EdgeSeq Mouse mRNA Tumor Response Panel

Larger sample input amounts must be diluted. Please consult the assay package insert and HTG EdgeSeq System User Manual for more details. 

FFPE Tissue One 5 µm section
Cells ≥3,000 cells
Extracted RNA from FFPE 35 ng
Extracted RNA from Frozen 10 - 35 ng

Applications

  • Preclinical disease modeling
  • Elucidation of molecular mechanisms of tumorigenesis
  • Compound screening and therapeutic response
  • Developing mouse mRNA biomarker signatures

Ordering Information

When placing an order, please specify the catalog number. The HTG EdgeSeq Mouse mRNA Assay is compatible with Illumina sequencers. 

Kit Configurations for use with Illumina Sequencers

916-010-208 HTG EdgeSeq Mouse mRNA Tumor Response Panel (2 X 8)
916-010-008 HTG EdgeSeq Mouse mRNA Tumor Response Panel (4 X 8)
916-010-224 HTG EdgeSeq Mouse mRNA Tumor Response Panel (1 X 24)
916-010-024 HTG EdgeSeq Mouse mRNA Tumor Response Panel (4 X 24)
916-010-096 HTG EdgeSeq Mouse mRNA Tumor Response Panel (1 X 96)

For Research Use Only. Not for Use in Diagnostic Procedures.

Request A Quote

Resources and Publications

Learn more about the HTG EdgeSeq Mouse mRNA Tumor Response Panel

Resources

HTG EdgeSeq Mouse mRNA Tumor Response Panel Gene List
Download pdf 118KB
View External Link

HTG EdgeSeq Mouse mRNA Tumor Response Panel Product Sheet
Download pdf 101KB

Publications

Targeting cardiac fibrosis with engineered T cells
Download pdf 13.4MB


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For further information about the HTG EdgeSeq Mouse mRNA Tumor Response Panel, please fill out the registration form below or call us at (877) 507-3259.

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Page last updated August 23, 2019