Assays
HTG EdgeSeq Pan B-Cell Lymphoma Panel

HTG EdgeSeq Pan B-Cell Lymphoma Panel

Measure gene expression of mRNA targets commonly associated with indolent and aggressive lymphomas to help identify lymphoma subgroups to elucidate the transcription response of disease state and drug therapy. With 298 gene targets, the HTG EdgeSeq Pan B-Cell Lymphoma Panel addresses the heterogeneity of B-Cell lymphomas, including published signatures and drug targets. Leveraging the sensitivity and dynamic range of next-generation sequencing (NGS), the HTG EdgeSeq Pan B-Cell Lymphoma Panel enables multiplex profiling from limited formalin-fixed, paraffin-embedded (FFPE) samples. The ability to work with small tissues is critical when considering that 10-15% of specimens in clinical practice do not qualify due to high sample requirements (PMID: 30248164). This extraction-free HTG EdgeSeq assay is automated on the HTG EdgeSeq system or available at our VERI/O lab as a service.

For Research Use Only. Not for Use in Diagnostic Procedures.

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Features and Benefits

  • Measure 298 transcripts in a single well:
    obtain a broad profile of genes associated with B-cell lymphomas from a single analysis
  • Extraction-free chemistry:
    proprietary sample preparation workflow that reduces bias and sample loss associated with extracted RNA
  • Low sample input:
    reliable results with as little as 6.0 mm2 tissue area per sample well
  • Simplified data analysis:
    determine the Cell of Origin predicted probability of GCB for diffuse large B-cell lymphomas using the fully integrated
    HTG EdgeSeq Reveal data analysis pipeline

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Sample Requirements and Options

Sample Type HTG EdgeSeq Pan B-Cell Lymphoma Panel

Larger sample input amounts must be diluted. Please consult the assay package insert and HTG EdgeSeq System User Manual for more details. 

FFPE Tissue One 5 µm section

Lymphoma Subtypes 

The Following Lymphoma Subtypes are targeted by the HTG EdgeSeq Pan B-Cell Lymphoma Panel:

 

Diffuse large B-cell lymphoma
Plasmablastic lymphoma
Mantle cell lymphoma
Chronic lymphocytic leukemia
Marginal zone lymphoma
Burkitt lymphoma
Primary mediastinal B-cell lymphoma
Lymphoplasmacytic lymphoma
Double hit lymphoma
Molecular high-grade lymphoma
Folicular lymphoma
Myeloma

Ordering Information

When placing an order, please specify the catalog number. The HTG EdgeSeq Pan B-Cell Lymphoma Panel is compatible with the Illumina sequencers in the U.S. and E.U.

Kit Configurations for use with Illumina Sequencers (US)

916-017-208 HTG EdgeSeq Pan B-Cell Lymphoma Panel (2x8)
916-017-008 HTG EdgeSeq Pan B-Cell Lymphoma Panel (4x8)
916-017-224 HTG EdgeSeq Pan B-Cell Lymphoma Panel (1x24)
916-017-024 HTG EdgeSeq Pan B-Cell Lymphoma Panel (4x24)
916-017-096 HTG EdgeSeq Pan B-Cell Lymphoma Panel (1x96)

Kit Configurations for use with Illumina Sequencers (EU)

916-017-208E HTG EdgeSeq Pan B-Cell Lymphoma Panel (2x8)
916-017-008E HTG EdgeSeq Pan B-Cell Lymphoma Panel (4x8)
916-017-224E HTG EdgeSeq Pan B-Cell Lymphoma Panel (1x24)
916-017-024E HTG EdgeSeq Pan B-Cell Lymphoma Panel (4x24)
916-017-096E HTG EdgeSeq Pan B-Cell Lymphoma Panel (1x96)

For Research Use Only. Not for Use in Diagnostic Procedures.

Request A Quote

Resources and Publications

Learn more about the HTG EdgeSeq Pan B-Cell Lymphoma Panel (coming soon)

Resources

HTG EdgeSeq Pan B-Cell Lymphoma Panel Gene List
Download pdf 51KB

HTG EdgeSeq Pan B-Cell Lymphoma Panel Product Sheet
Download pdf 189KB

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For further information about the HTG EdgeSeq Pan B-Cell Lymphoma Panel, please fill out the registration form below or call us at (877) 507-3259.

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Page last updated June 29, 2020