HTG Therapeutics
The initial focus of HTG Therapeutics will be to identify development candidates targeting RNA or RNA modifying proteins, which could be relevant in areas such as oncology, immunology, diabetes, and rare disease. HTG’s EdgeSeq and Epi-EdgeSeq technology is a foundational element in our drug discovery programs. It enables a more highly resolved view of the transcriptome, especially aberrations in physiological states leading to disease. Utilizing recent advancements in data science, we seek to create better therapeutic candidates by assimilating RNA profiling directly into the drug discovery process.
Technology
HTG Therapeutics will leverage its transcriptomic and epi-transcriptomic profiling technology to improve the existing drug discovery process. This process currently produces a profile with close to 42,000 data points per sample in three independent data sets which includes the ability to detect changes in RNA modifications, such as N6-methyladenosine (m6A), which has been increasingly implicated in various disease states.
Drug Discovery Process
By leveraging HTG's unique profiling technologies earlier in the drug discovery process, HTG Therapeutics is expected to generate lead compounds faster, and with superior efficacy and toxicity profiles.
Drug Discovery Pipeline
HTG Therapeutics will identify development candidates targeting RNA and RNA-modifying proteins, targets relevant in a wide range of diseases of unmet therapeutic need. The profiling of these diseases using the HTG EdgeSeq technology is an essential element in guiding these efforts. From hit to lead clinical candidate- HTG seeks to bring to the forefront the power of transcriptome profiling and data science to generate insights factoring into the selection of improved therapeutic candidates entering clinical trials.
HTG Therapeutics News & Events
HTG Expands Therapeutics Team
Veteran Drug Developer Stephen Barat, Ph.D. Joins to Head Company’s Therapeutics Division TUCSON, Ariz. , Oct. 05, 2021 (GLOBE NEWSWIRE) – HTG Molecular Diagnostics, Inc. (Nasdaq: HTGM) (HTG), a life science company advancing precision medicine through its innovative transcriptome-wide profiling…
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HTG Molecular Diagnostics to Present at the Cantor Fitzgerald Virtual Global Healthcare Conference
TUCSON, Ariz. , Sept. 21, 2021 (GLOBE NEWSWIRE) – HTG Molecular Diagnostics , Inc. (Nasdaq: HTGM) (HTG), a life science company whose mission is to advance precision medicine, today announced that company management will present in a fireside chat in Cantor Fitzgerald’s Virtual Global Healthcare…
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HTG Molecular Diagnostics to Present at H.C. Wainwright’s 23rd Annual Global Investment Conference
TUCSON, Ariz. , Sept. 08, 2021 (GLOBE NEWSWIRE) – HTG Molecular Diagnostics , Inc. (Nasdaq: HTGM) (HTG), a life science company whose mission is to advance precision medicine, today announced that company management will participate in H.C. Wainwright’s 23rd Annual Global Investment Conference ,…
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Page last updated August 05, 2021