Molecular Profiling and More for Your Samples

VERI/O Laboratory Services supports retrospective molecular profiling studies for biopharma clients and  translational medicine researchers. In addition to sample processing services using HTG’s on-market products, we also offer early access to our newest technologies, such as our direct sequencing chemistry that run exclusively in the VERI/O lab.  

VERI/O laboratory also provides assay development, sample accessioning, and data analysis services to support studies. 

Let VERI/O Laboratory Services be an extension of your organization.  Take advantage of the benefits of our
HTG EdgeSeq technology without the up-front capital expense.

VERI/O Laboratory Services:

  • Retrospective sample processing
  • Pilot studies
  • Custom assay development
  • Disease-specific validation studies

For custom assays, please contact HTG directly.

Learn More

Service Offerings

VERI/O Laboratory Services accepts a wide variety of clinical samples for testing, including formalin-fixed, paraffin-embedded (FFPE) tissue, plasma/serum, PAXgene, extracted RNA, and cells. Sample types and amounts are specific to each assay and customer project.

“HTG has been a true partner and collaborator in our drug development program and we truly appreciate their support to meet the regulatory filing deadline for one of our key drug products.”
~ Senior Manager, Clinical Biomarkers—Oncology, Global Pharma Partner

How VERI/O Laboratory Services Fit in the Drug Development Process

Preclinical & Retrospective Prospective Patient Enrollment Companion Diagnostics (CDx)




Analytical validation Labeled & distributed under approved clinical protocol Global commercialization
Global regulatory approvals
Clinical validation
VERI/O Laboratory Services or your lab Qualified Service Provider (QSP) or Contract Research Organization (CRO) Laboratories worldwide


VERI/O Laboratory Workflow

  • Molecular profiling expertise - highly trained and dedicated staff delivering high-quality data leveraging the advantages of the HTG EdgeSeq technology.
  • Focused on turnaround times - receive a customized report on tens to thousands of biomarkers to meet your timelines.
  • Deferred investment cost - all the advantages of targeted next-generation sequencing (NGS)-based results without the capital investments, training, and labor costs.

Products/Services Comparison

There are several ways to take advantage of the unique benefits of the HTG EdgeSeq technology. 


  VERI/O Laboratory Services In Your Lab Using The HTG EdgeSeq System HTG Qualified Service Providers
HTG Transcriptome Panel Yes Yes Yes
HTG EdgeSeq Custom Assay Yes Yes Yes
HTG EdgeSeq DLBCL Cell of Origin Assay Yes Yes Yes
HTG EdgeSeq Immune Response Panel Yes Yes Yes
HTG EdgeSeq miRNA Whole Transcriptome Assay Yes Yes Yes
HTG EdgeSeq Mouse mRNA Tumor Response Panel Yes Yes Yes
HTG EdgeSeq Oncology Biomarker Panel Yes Yes Yes
HTG EdgeSeq Pan B-Cell Lymphoma Panel Yes Yes Yes

Applications in Immuno-Oncology

Applications Features Benefits
Tumor microenvironment

Measure the gene expression of microdissected tumor subsections such as vasculature, stroma, and tumor from a single FFPE tissue section

Develop insights into the tumor biology

  • Tumor-infiltrating lymphocyte (TIL) composition and density
  • Interferon gamma expression levels
  • T-cell effector status
  • Cytokine expression
  • Immunomodulation
Cytokine / chemokines

Simultaneous monitoring of multiple chemokines and cytokines within cancer tissue and associated stroma

Spatial-temporal mapping of immune-stimulatory or suppressant signals

Resistance / relapse system biology

Characterization of pathway modulators that impact cancer drug response

  • Better understanding of how disease progression is tied to underlying tumor biology
  • Investigate alternative clinically actionable drug targets for late stage cancer patients

Measure the expression of cytokeratins, clusters of differentiation, epithelial genes and other histological markers

  • Identify or confirm histological grading of critical specimens
  • Sub-classify cancers into subtypes
Signaling pathways

Assess the status of pathways such as:

  • Angiogenesis/vasculature
  • Apoptosis
  • Epithelial-mesenchymal transition
  • Stem cell markers

Grouping tumors via common dysregulated molecular pathways can provide deeper molecular understanding of tumors

Other Applications

Applications Features Benefits
Immune checkpoint expression within molecular subtyped diffuse large B-cell (DLBCL) tumors

Characterization of immunocheckpoint factors together with tumor infiltrating lymphocyte (TIL) markers within DLBCL tumors classified via subtype

Investigate tumor immune-responsiveness of DLBCL tumors

miRNA profiling of tumors and liquid biopsies

Identify tumor miRNA-based signatures from different sample types using whole transcriptome miRNA profiling

Identify tissue-based miRNA profiles that can be translated to blood samples

Immunophenotyping immune cells

Pseudo-flow analysis using cluster of differentiation (CD)-based markers

Sensitivity and ability to multiplex above applications/markers

Subtyping DLBCL tumors

Characterize cases as Activated B-Cell Type (ABC) vs. Germinal Center B-Cell Type (GCB)

Stratify groups for biomarker and drug development

Sample Types and Input Requirements

Please contact your HTG Account Representative or for information regarding VERI/O sample input requirements

Learn More

For more information about VERI/O Laboratory Services, please fill out the form below. Or call us at (877) 507-3259.

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Page last updated January 25, 2023

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