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Role of miRNAs in Metabolic Vascular Disease

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Peripheral artery disease (also called peripheral arterial disease or PAD) is a common vascular condition in which narrowed arteries reduce blood flow to the arms or legs.

Critical limb ischemia (CLI) is a severe blockage in the arteries of the lower extremities, which markedly reduces blood-flow.

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Understanding Volcano Plots

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volcano plot is useful for identifying events that differ significantly between two groups of experimental subjects. The name volcano plot comes from its resemblance to a volcanic eruption with the most significant points at the top, like spewed pieces of molten lava.

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RNA Based Gene Expression Profiling

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There is a growing interest in research into different types of RNAs as they are all puzzle pieces needed to form a complete picture of epigenetics. Currently, mRNA and miRNA molecules are most commonly used for RNA based GEP.

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Transcriptome-informed Drug Design

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HTG EdgeSeqTM (EdgeSeq) technology and HTG Transcriptome Panel (HTP) produce a comprehensive and quantitative map of a cell’s transcriptomic response.

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Introduction to Gene Expression Profiling

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The central dogma of biology describes the process by which information coded in genes is used to create proteins. DNA transcription produces RNA, then RNA translation makes proteins. This process is known as gene expression.

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HTG at ASCO 2022

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ASCO 2022, the major conference post-pandemic in which HTG participated, was a huge success! The power of HTG technology was showcased by scientist from across the globe at the American Society of Clinical Oncology(ASCO) 2022 Annual Meeting, held at the McCormick Place in Chicago, Illinois on June 3-7. 

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COVID-19 Pathogenesis, Lessons Learned from Lymph Nodes

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Long-lasting clinical presentation of COVID-19, also called long COVID, is characterized by a wide range of symptoms that appear in a significant number of COVID-19 patients after recovery. Understanding the pathogenesis of COVID-19 is therefore critical to the development of effective therapeutics and predicting immune response in patients.

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Page last updated September 27, 2022