HTG EdgeSeq system
The HTG EdgeSeq system automates our novel target capture and library prep chemistry and helps enable fast and easy use of next-generation sequencers (NGS) for microRNA (miRNA), messenger RNA (mRNA) and fusions analysis. The HTG EdgeSeq system simplifies library and sample prep for targeted sequencing enhancing productivity and ease of use. The HTG EdgeSeq extraction-free chemistry also can significantly reduce sample input requirements, especially from formalin-fixed, paraffin embedded (FFPE) samples. By using the HTG EdgeSeq system, scientist can go from raw sample to sequencing-ready libraries in ~28 hours with less than a few hours of hands-on time. The HTG EdgeSeq system also eliminates biases associated with DNA/RNA extraction, size selection, cDNA synthesis, and adapter ligation. This helps ensure libraries prepared from precious samples like FFPE tissue, or plasma, can be generated reproducibly. The HTG EdgeSeq informatics package greatly simplifies data analysis.
Learn More About the HTG EdgeSeq Products and Chemistry
HTG's Nature.org webcast: Overcoming the challenges of NGS-based RNA profiling using limited, precious samples.
Automated high fidelity miRNA expression profiling using nuclease protection coupled with next generation sequencing
HTG EdgeSeq Oncology Biomarker Assay (OBP), an NGS-based gene expression assay for measuring 2,532 oncology-related genes in FFPE tissue in different sample types
Targeted RNA Sequencing for simultaneous expression profiling and detection of gene rearrangements in FFPE biopsies
Evaluation of normalization methods for miRNA sequencing data generated with qNPA
For Research Use Only. Not for use in diagnostic procedures.