HTG EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin Assay (DLBCL COO)

The HTG EdgeSeq DLBCL Cell of Origin Assay provides a simple, automated gene expression-based assay to subtype diffuse large B-cell lymphoma (DLBCL) tissues.

DLBCL is a broad grouping of lymphomas generally diagnosed by cell morphology and immuno-phenotype. The traditional diagnosis of DLBCL does not, however, establish the DLBCL sub-type of the tumor.

The HTG EdgeSeq DLBCL Cell of Origin Assay provides a subtype classifier that identifies Activated B-Cell like (ABC), Germinal Center B-cell like (GCB) or “unclassified”. The classification software was trained and validated on over 250 samples previously sub-typed by microarray-based gene expression profiling.

In addition to DLBCL classification, a single section of 5 µm FFPE tissue provides expression data for many potential drug targets and lymphoma lineage markers.

For additional questions regarding the HTG EdgeSeq DLBCL COO Assay please contact us at dlbcl@htgmolecular.com or orders@htgmolecular.com

For Research Use Only.  Not for Use in Diagnostic Procedures.

Resources

HTG EdgeSeq DLBCL COO Assay brochure

Next-Generation Sequencing for DLBCL Classification (presented at ASCO 2016)

 

 

Last updated: 03/10/2017 - 13:30

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