HTG EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin Assay (DLBCL COO)

The HTG EdgeSeq DLBCL Cell of Origin Assay provides a simple, automated gene expression-based assay to subtype diffuse large B-cell lymphoma (DLBCL) tissues.

DLBCL is a broad grouping of lymphomas generally diagnosed by cell morphology and immuno-phenotype. The traditional diagnosis of DLBCL does not, however, establish the DLBCL sub-type of the tumor.

The HTG EdgeSeq DLBCL Cell of Origin Assay provides a subtype classifier that identifies Activated B-Cell like (ABC), Germinal Center B-cell like (GCB) or “unclassified”. The classification software was trained and validated on over 250 samples previously sub-typed by microarray-based gene expression profiling.

In addition to DLBCL classification, a single section of 5 µm FFPE tissue provides expression data for many potential drug targets and lymphoma lineage markers.

For additional questions regarding the HTG EdgeSeq DLBCL COO Assay please contact us at or

For Research Use Only.  Not for Use in Diagnostic Procedures.


HTG EdgeSeq DLBCL COO Assay brochure

Next-Generation Sequencing for DLBCL Classification (presented at ASCO 2016)



Last updated: 03/10/2017 - 13:30

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